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发布时间:2021年09月16日 08:23 来源: 作者: 浏览次数:


肖竹平,男,教授,硕士生导师,湖南省药学学科带头人,湖南省121创新人才培养工程人选,湖南省青年骨干教师。现任武陵山地区民族药解析与创制湖南省工程实验室主任、湖南省湘西特色植物资源综合开发利用工程技术研究中心副主任,湖南省化工学会理事、民族医药教育专业委员会常务理事。近年来主持国家自然科学基金、湖南省自然科学基金和湖南省县域经济重大专项等6项。在药物设计与生物活性领域取得了一系列创新性进展,相关的研究成果形成了100余篇学术论文在J. Enzyme Inhib. Med. Chem, Eur. J. Pharm. Sci,Bioorg. Med. Chem,中国生态农业学报等国内外著名刊物发表。获得湖南省自然科学奖等2项,获专利授权13项。主持国家自然科学基金3项、湖南省自然科学基金2项、湖南省县域经济重大专项1项。

代表性论文

1. Wei-Yi Li, Wei-Wei Ni, Ya-Xi Ye, Hai-Lian Fang, Xing-Ming Pan, Jie-Ling He,Tian-Li Zhou, Juan Yi, Shan-Shan Liu, Mi Zhou, Zhu-Ping Xiao* and Hai-Liang Zhu.N-monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biologicalevaluation.J. Enzyme Inhib. Med. Chem., 2020, 35(1), 404-413. (IF:4.7)

2. Qi Liu, Wei-Wei Ni, Zhen Li, Cai-Fu Bai, Dan-Dan Tan, Chang-Jun Pu, Dong Zhou,Qing-Peng Tian, Ni Luo, Kai-Li Tan, Le Dai, Yuan Yan, Yong Pei, Xian-Hui Li,Zhu-Ping Xiao* and Hai-Liang Zhu. Resolution and evaluation of3-chlorophenyl-3-hydroxypropionylhydroxamic acid as antivirulence agent withexcellent eradication efficacy in Helicobacter pylori infected mice.Eur. J. Pharm. Sci.,2018, 121, 293–300. (IF:3.5)

3. Qi Liu, Wei-kang Shi, Shen-Zhen Ren, Wei-wei Ni, Wei-yi Li, Hui-min Chen, PeiLiu, Jing Yuan, Xiao-su He, Jia-Jia Liu, Peng Cao, Pu-Zhen Yang, Zhu-Ping Xiao*and Hai-Liang Zhu. Arylamino containing hydroxamic acids as potent ureaseinhibitors for the treatment of helicobacter pylori infection.Eur. J. Med. Chem., 2018,156, 126-136. (IF:4.8)

4. Wei Wei, Qi Liu, Zhen-Zhen Li, Wei-Kang Shi, Xing Fu, Jia Liu, Xuan Zhu,Xiao-Cong Wang, Ning Xu, Teng-Fei Li, Fu-Rui Jiang, Zhu-Ping Xiao* andHai-Liang Zhu. Synthesis and evaluation of adenosine containing3-arylfuran-2(5H)-ones as tyrosyl-tRNA synthetase inhibitors.Eur. J. Med. Chem.,2017, 133, 62-68. (IF:4.8)

5. Zhu-Ping Xiao*, Wei Wei, Peng-Fei Wang, Wei-Kang Shi, Na Zhu, Me-Qun Xie,Yu-Wen Sun, Ling-Xia Li, Yong-Xiang Xie, Liang-Song Zhu, Nian Tang, Hui Ouyang,Xian-Hui Li, Guang-Cheng Wang and Hai-Liang Zhu. Synthesis and evaluation ofnew tyrosyl-tRNA synthetase inhibitors as antibacterial agents based on aN2-(arylacetyl)glycinanilide scaffold.Eur. J. Med. Chem., 2015, 102, 631-638. (IF:3.9).

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